Charles Louis Davis and Samuel Wesley Thompson DVM Foundation

For the Advancement of Veterinary and Comparative Pathology

info@cldavis.org | Phone: 847-367-4359 | Fax: 847-247-1869
  • 44th Annual Gross Review Course

    Learn all about gross lesions in domestic, laboratory, and exotic animals.

  • 2017 Current Lab Animal Science Seminar / Pathology of Lab Animals Course

    Recognize and interpret conditions which may affect experimental results or alter the health of laboratory animals.

  • Annual Diagnostic Pathology Symposium: Diagnostic Renal Pathology

    Learn about glomerular pathology, glomerular ultrastructure, and pathology of tubulointerstitial disease.

  • Annual Zoo & Wildlife Pathology Workshop

    The theme of this year is fungal diseases.

  • Argentinean Division Seminar

    Dr. Donal O'Toole (second from left) is demonstrating lesions, and Dr. Melissa Macias (second from right) is translating into Spanish at the 10th seminar of the Argentinean Division of the Foundation.

  • Chilean Seminar

    Participants of the 4th Chilean Seminar of the Foundation on the campus of the University of Chile in Santiago de Chile in August 2016.

  • European Symposium

    The European Symposium of the Foundation was held in Bologna, Italy, in September 2016.

  • Northeast Day Seminar

    Janssen R&D (J&J Pharmaceuticals) and the Davis-Thompson sponsored and hosted the Northeast Day Seminar at Spring House, Pennsylvania in September 2016.

CE Portal

Course ID: 166312
Title: Pathology of the Musculoskeletal System of the Dog


Length: 00:45:00
Author: Dr Bruce Williams DVM
Description: This RACE-accredited lecture discusses the pathologic features of the musculoskeletal system of the dog.

Noah's Arkive

The Foundation is proud to make Noah's Arkive, a searchable collection of veterinary pathology images, available online at no cost. Special thanks to the University of Georgia for transferring the database and image collection to the Foundation!

Random Image:

CL Davis Diagnostic Exercises

The main goal of these Diagnostic Exercises is to provide interesting cases, focusing on the gross pathological lesions and associated histopathologic or cytologic findings. This material can be of great use for veterinary students, in-training pathologists, and ACVP diplomates alike.

There will be one contribution per month of the year; anyone may contribute. To do so, please contact Dr. Vinicius Carreira at vinicius.carreira@gmail.com to identify a convenient date for your submission and to receive templates to be used. Spots will be filled out on a first-come first-served basis.

Exercise Thumbnail Answer
Click here for case history Click here for case synopsis

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New in Noah from the archives of the Armed Forces Institute of Pathology.

Tissue from a duck.

Name an associated condition: Zinc toxicosis

Name an associated lesion: Pancreatic necrosis

Comment: From a eider duck - original image from the National Zoo. This coin was likely tossed in an exhibit for "good luck", but was not good luck for this duck that ingested it.

Pennies are primarily composed of zinc, with only a thin patina of copper. Affected animals may demonstrate pancreatic necrosis, renal tubular necrosis, and or hemolytic anemia resulting from the leaching of zinc from pennies in the acidic pH of the stomach.

Pancreatic necrosis is the classic lesion associated with zinc toxicosis, as the pancreas stores significant amounts of zinc and is actually involved in zinc metabolism. But too much overwhelms cellular metallothioneins, resulting in oxidative stress. Another theory of cellular damage postulates that free zinc may actually activate trypsinogen.

Either way, keep your pennies in your pockets!
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New today in Noah - from the archives of the Armed Forces Institute of Pathology.

Tissue from a sea lion pup.

Morphologic diagnosis: Severe bilateral hyphema.

Cause: Leptospira pomona

Comment: Periodic outbreaks of Leptospira pomona occur in California sea lions. In addition to characteristic renal lesions, it may result in reproductive failure, abortions and still borns. Affected pups have extensive subcutaneous hemorrhage as well as hyphen, which has resulted in the term, "red eye" for this disease.
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I will be speaking at RTC@ACT on November 4 about Tg.rasH2 model. If you are attending please join me. ... See moreSee less

New today in Noah - again from Fabrizio Grandi - he is on a hot streak!

Tissue from a dog.

Morphologic diagnosis: MULTIFOCAL TO COALESCING XANTHOGRANULOMATOUS GLOSSITIS; CANINE ATYPICAL MUCOSA-ASSOCIATED XANTHOMAS.

9 YEARS-OLD SHI-TZU DOG. Canine atypical mucosa-associated xanthoma is a rare or underdiagnosed disorder characterized by solitary to multiple papillary nodules or raised plaques located on dorsal or ventral surface of the tongue. Microscopically, these lesions are characterized by the presence of clusters of large, vacuolated, lipid-laden macrophages covered by a hyperplastic, hyperkeratotic, squamous epithelium. In dogs, xanthomas can be associated with hyperlipidemia, diabetes mellitus, hypothyroidism, and hyperadrenocorticism.

References 1. Balme E. et al. Multiple atypical mucosal xanthomas in a dog similar to human verruciform xanthoma. J Vet Diagn Invest 21:124–128 (2009).
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